News & Your Opinion

Growth Factor-Loaded Microparticles Enhance 3D Bioprinted Muscle

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2 years ago

Last updated: 17/10/2023 at 06:49 AM


Researchers at the Terasaki Institute in Los Angeles have developed a new method to create 3D printed muscle constructs with enhanced muscle cell alignment and maturation. The technique involves creating microparticles loaded with insulin-like growth factor (IGF) using a microfluidic platform. Then, these particles are included in a bioink that also incorporates myoblast cells and a gelatin-based hydrogel. Once 3D printed, the resulting constructs show enhanced cell growth, elongation, and alignment, and in some cases even began to spontaneously contract after a ten day incubation. The Ter

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